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Method of Neoantigen-Reactive T Cell Receptor (TCR) Isolation from Peripheral Blood of Cancer Patients

National Institutes of Health Early / Discovery Cell/Gene Therapy
Probability of Success

14% · grade C · Medium data confidence

Model PoS 14% (grade C, medium data confidence). Strongest signals: IP position, Indication pull. Biggest drag: Translational evidence.

Data maturity (22%) 36

Early / Discovery; limited public evidence of validation.

IP position (16%) 72

Patent filed/pending -- prosecution ongoing.

Modality feasibility (14%) 55

Cell/gene therapy -- high upside, heavy manufacturing and regulatory load.

Indication pull (14%) 77

Oncology, Immunology -- active buyer appetite.

Competitive whitespace (12%) 78

Under-served segment; crowded oncology field; multi-modal differentiation.

Translational evidence (12%) 54

Public evidence mentions: patient.

Licensing readiness (10%) 94

Listed as available for licensing; established tech-transfer office; 1 public source link(s).

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