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A Broadly Protective Human Antibody for GI Genogroup Noroviruses

National Institutes of Health Preclinical Biologic
Probability of Success

26% · grade B · Medium data confidence

Model PoS 26% (grade B, medium data confidence). Strongest signals: Data maturity, IP position. Biggest drag: Translational evidence.

Data maturity (22%) 64

Preclinical; in vivo data, human data.

IP position (16%) 72

Patent filed/pending -- prosecution ongoing.

Modality feasibility (14%) 66

Biologic/antibody -- solid path but higher CMC burden.

Indication pull (14%) 75

Infectious Disease, Immunology -- active buyer appetite.

Competitive whitespace (12%) 86

Under-served segment; multi-modal differentiation.

Translational evidence (12%) 62

Public evidence mentions: human, in vivo.

Licensing readiness (10%) 94

Listed as available for licensing; established tech-transfer office; 1 public source link(s).

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