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LicenseRx asset brief

Thioamide-modified peptides for stabilized therapeutics and drug development

University of Pennsylvania Preclinical Small Molecule
Probability of Success

25% · grade C · Medium data confidence

Model PoS 25% (grade C, medium data confidence). Strongest signals: Data maturity, Indication pull. Biggest drag: Translational evidence.

Data maturity (22%) 62

Preclinical; in vivo data, PK data.

IP position (16%) 45

No clear patent status in public data -- treat IP as unpriced until counsel confirms.

Modality feasibility (14%) 66

Biologic/antibody -- solid path but higher CMC burden.

Indication pull (14%) 74

Cardiometabolic -- active buyer appetite.

Competitive whitespace (12%) 74

Multi-modal differentiation.

Translational evidence (12%) 54

Public evidence mentions: in vivo.

Licensing readiness (10%) 94

Listed as available for licensing; established tech-transfer office; 1 public source link(s).

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