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Transplantation of defined gut microbial consortia in the treatment of urease associated diseases

University of Pennsylvania Preclinical Biologic
Probability of Success

25% · grade C · Medium data confidence

Model PoS 25% (grade C, medium data confidence). Strongest signals: Data maturity, Indication pull. Biggest drag: IP position.

Data maturity (22%) 59

Preclinical; human data.

IP position (16%) 45

No clear patent status in public data -- treat IP as unpriced until counsel confirms.

Modality feasibility (14%) 66

Biologic/antibody -- solid path but higher CMC burden.

Indication pull (14%) 74

Inflammation, Neurology -- active buyer appetite.

Competitive whitespace (12%) 68

Average room to differentiate vs. incumbents.

Translational evidence (12%) 62

Public evidence mentions: human, patient.

Licensing readiness (10%) 94

Listed as available for licensing; established tech-transfer office; 1 public source link(s).

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